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The US Food and Drug Administration is located in Washington, DC, and Rockville, Maryland. It has a large organization with branches throughout the country. To strengthen drug quality management, the FDA divides the country into six regions, namely the Pacific (San Francisco, Seattle, Los Angeles), Southwest (Dallas, Denver, Kansas), Central and Western (Chicago, Minneapolis, Detroit). Northeast, Boston, New York, Buffalo, Mid-Atlantic (Philadelphia, Cincinnati, Newark, Baltimore), Southeast (Atlanta, Nashville, New Orleans, Orlando, Puerto Rico, Saint-Jean). A district is set up in each district, and several districts are also set up under the district. The Pacific Region is located in San Francisco, the Southwest Region is located in Dallas, the Central and Western Region is located in Chicago, and the Northeast Region is located in Boston, the location of the Mid-Atlantic Region. Philadelphia, the location of the Southern District, is located in Atlanta.

The Center for Food Safety and Applied Nutrition, also known as CFSAN, is a national food field investigation agency and is one of six product-oriented centers that fulfill the Food and Drug Administration's (FDA) mandate. As a scientific management agency, the FDA's role is to ensure the safety of food, cosmetics, pharmaceuticals, biological agents, medical devices and radioactive products produced or imported in the United States. It is one of the first federal agencies to protect consumers as the primary function. The institution is closely related to the lives of every American citizen. Internationally, the FDA is recognized as one of the world's largest food and drug regulatory agencies. Many other countries promote and monitor the safety of their domestic products by seeking and receiving FDA assistance. The FDA is one of the executive agencies established by the US government in the Department of Health and Human Services (DHHS) and the Department of Public Health (PHS). The FDA's mission is to promote and protect the health of the public by ensuring the safety, hygiene, health and proper labeling of the US food and the safe and correct identification of the cosmetics.